Posting Summary: The Engel lab in the Department of Pediatrics, Division of Hematology Oncology at the University of Virginia is seeking a post-doctoral Research Associate to join the team focused on molecular determinants of leukemia pathogenesis and development of new agents to treat leukemia in children, adolescents and adults.
In the Engel lab, we focus on signal transduction pathways and transcriptional regulators that govern cell fate specification in normal and malignant hematopoiesis. Our active projects range from the most intricate molecular interrogation of structure/function relationships and their consequences in hematopoiesis to pre-clinical modeling and new therapeutic agent discovery and evaluation for leukemia indications, including clinical trial development. Translation of laboratory findings is an important goal for us, and we believe strongly that detailed molecular understanding of normal and malignant biology is the most probable means to achieve this.
A PhD by start date is required. Have strong skills in diverse molecular biology and protein biochemistry techniques, be adept at cell culture and in situ manipulation of gene expression using retro/lentiviral transduction/RNAi or CRISPR/Cas9 strategies and have a familiarity with or willingness to acquire basic bioinformatics skills. Experience with mouse transplantation models, including xenotransplants with primary samples from leukemia patients is highly desired. Additionally, candidates should have strong communication skills, both written and verbal, work effectively in a collaborative and service-oriented setting and have the passion and drive to propel their project(s) forward. Publication of impactful research, including first authorships of primary literature, is required. The fellow will work closely with the Principle Investigator and colleagues to develop their scientific and communications skills further with the goal of securing extramural funding critical for the fellow's future success as an independent investigator.
The University of Virginia and the Emily Couric Cancer Center are located in Charlottesville, Virginia nestled among the Blue Ridge Mountains, and offer a quality of life unparalleled in the United States. The community and surrounding areas are steeped in the history and heritage of America and there is easy access to some of the country's most vibrant cities. Washington, DC is just a short train ride away! Residents have access to outstanding theater, fine arts, music, sports, shopping, and restaurants representing cuisines from around the world. The outdoor living in and around Charlottesville is second to none! Charlottesville is serviced by an easily accessible airport that is the jumping off point for destinations around the globe. Our city is growing and economically robust. It is safe and affordable, enabling all of the advantages of cosmopolitan living removed from the challenges of big city living. It is a wonderful place to raise a family.
To apply please visit: https://jobs.virginia.edu/applicants/Central?quickFind=85882. Create a candidate profile and attach your CV and 3 references.
For additional information please contact Greg Haskins at email@example.com.
The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans and persons with disabilities are encouraged to apply.
Internal Number: 353_85882
About University of Virginia
Founded by Thomas Jefferson, the University of Virginia opened in 1825 as the nation's first public university. A longstanding dedication to preeminence in both scholarship and teaching; top ranking in global satisfaction, collegiality and work/family issues on the COACHE survey of early career faculty; a commitment to excellence that is integrally connected with diversity and a broad array of benefits make the University of Virginia a prime choice for both faculty and staff. The University of Virginia is located in the small cosmopolitan city of Charlottesville near the Blue Ridge Mountains, 70 miles from Richmond and 110 miles from Washington, D.C. The University of Virginia remains the No. 2 best public university in the 2013 edition of the U.S. News and World Report rankings. In the 14 years since U.S. News began ranking public universities as a separate category, U.Va. has ranked either No. 1 or No. 2. U.Va. continues to rank in the Top 25 among the best of all national universities, public and private.