Post-Doctoral Fellow in Vaccine Development - (1900016R)
Center for Vaccine Development and Global Health (CVD), Immunology Group, Department of Pediatrics, University of Maryland School of Medicine.
The CVD involves scientists and physicians in all phases of vaccine development. The CVD has earned an international reputation for genetically engineering and testing vaccines against a wide variety of enteric infections. Based in the School of Medicine at the University of Maryland, Baltimore, the CVD was established in the 70's as one of the first facilities to evaluate vaccines in community volunteers. It is one of only a handful of vaccine centers in the world engaged in the full range of vaccinology: from basic science through vaccine development, immunological studies, clinical evaluation and field studies.
We are seeking postdoctoral fellows who will participate in immunological studies directed at understanding immune responses and uncovering immunological correlates of protection following immunization and infection in humans with the long-term goal of accelerating the development of novel vaccines. Studies will include exploration of the mechanisms operative in the generation of systemic and mucosal immunity in children, young adults and the elderly and their relationship to the gut microbiota. These studies will involve participants immunized with licensed or investigational attenuated and subunit vaccines, as well as volunteers challenged with wild-type organisms. Studies will involve the use of advanced technologies and instrumentation such as high-parameter flow cytometry and mass cytometry (40+ parameters/cell) with a focus on complex data analyses, as well as the performance of a variety of molecular biology and immunological techniques depending on the research questions being addressed. These include, among others, functional assays (e.g., cell purification, proliferation, cytotoxic T cell activity, Elispot, regulatory T cell activity, identification of T cell epitopes, B cell maturation and function), single cell transcriptomics (scRNA-seq), epigenetic landscape determinations, and role of microRNAs (miRNA) in the regulation of immunity.
The successful candidate should have a Ph.D. in Microbiology/Immunology and/or M.D. degree, experience in the study of immunological mechanisms, a strong publication track record, be highly motivated, have outstanding organizational skills and great attention to detail, high scientific integrity and rigor, excellent written and oral communication skills and hold a valid VISA to work in the US. A strong background in bioinformatics and systems biology analyses, as well as experience in flow and mass cytometry and other immunological techniques is highly desirable. The CVD is a nurturing environment that focuses on training and supporting post-doctoral fellows in their path towards independence. Post-doctoral fellowships are initially for one year, but they may be renewed annually based on progress for up to a maximum of 5 years.
Please send curriculum vitae, a brief outline of relevant research experience and interests and the names of three references via e-mail to Marcelo B. Sztein M.D., Professor of Pediatrics; Associate Director for Basic and Translational Research, Chief, Cellular Immunology Section, CVD, and Director of the University of Maryland Flow Cytometry and Mass Cytometry Core Facility; at email@example.com. Further information about the CVD can be found at: http://medschool.umaryland.edu/CVD/ .
UMB is an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law or policy.
Job: Postdoctoral Fellows
Organization: School of Medicine - Centers/Programs/ORCs
Job Posting: Sep 4, 2019
Internal Number: 132701
About University of Maryland, Baltimore
The University of Maryland, Baltimore (UMB) is the State's public health, law and human services university devoted to excellence in professional and graduate education, research, patient care, and public service. As a diverse community of outstanding faculty, staff and students, and using state-of-the-art technological support, we educate leaders in health care delivery, biomedical science, global health, social work and the law. We emphasize interdisciplinary education and research in an atmosphere that explicitly values civility, diversity, collaboration, teamwork and accountability. By conducting internationally recognized research to cure disease and to improve the health, social functioning and just treatment of the people we serve, we foster economic development in the City, State, and nation. We are committed to ensuring that the knowledge we generate provides maximum benefit to society and directly enhances our various communities.