Required Qualifications: (As evidenced by an attached resume)
Doctoral degree (Foreign equivalent or higher degree) in Biology or related field. Research experience with transgenic murine models and hematopoietic stem/progenitor cell culture.
Solid experience and first author publications in molecular biology or stem cell biology.
Brief Description of Duties:
The Zhan lab focuses on the pathogenesis and treatment of myeloproliferative neoplasms (MPNs). The MPNs are clonal stem cell disorders characterized by hematopoietic stem/progenitor cell (HSPC) expansion and overproduction of mature blood cells. The acquired mutation JAK2V617F plays a central role in these disorders, but the precise molecular mechanisms responsible for MPN HSPC expansion are not fully understood, limiting the effectiveness of current treatments. Using molecular and genetic techniques in both MPN patient samples and transgenic murine models, our lab studies how the hematopoietic microenvironment cells (e.g. endothelial cells, megakaryocytes) contribute to the neoplastic stem cell expansion in MPNs. The ultimate goal of our research is to understand the fundamental principles of stem cell biology and develop more effective therapies for patients with MPNs and other hematologic malignancies.
The Postdoctoral Associate is dedicated to support basic science and pre-clinical research. The Postdoctoral Associate must possess a strong work ethic, creativity and enthusiasm, as well as effective written and verbal communication skills. The selected candidate will be responsible for the following:
Plan experiments and technical requirements, prepare and test specimens.
Analyze data present the results at various scientific meetings, prepare manuscripts and grants.
Maintains laboratory equipment/supplies/facilities. Execute the administrative aspects of the study plan including preparing research-related documents.
The Research Foundation of SUNY is a private educational corporation. Employment is subject to the Research Foundation policies and procedures, sponsor guidelines and the availability of funding. FLSA Exempt position, not eligible for the overtime provisions of the FLSA. Minimum salary threshold must be met to maintain FLSA exemption. ** Evening and weekend work will be required at times.
Long Island's premier academic medical center, Stony Brook Medicine represents Stony Brook University's entire medical enterprise and integrates all of Stony Brook's health-related initiatives: education, research and patient care. It encompasses Stony Brook University Hospital, Stony Brook Children's Hospital, the five Health Sciences schools -- Dental Medicine, Health Technology and Management, Renaissance School of Medicine, Nursing and Social Welfare -- as well as the major centers and institutes, programs and more than 50 community-based healthcare settings throughout Suffolk County. With 603 beds, Stony Brook University Hospital serves as Suffolk County's only tertiary care center and Regional Trauma Center. Stony Brook Children's, with more than 180 pediatric specialists in 30 specialties, offers the most advanced pediatric specialty care in the region.
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FROM ITS BEGINNINGS A HALF-CENTURY AGO, STONY BROOK UNIVERSITY HAS BEEN CHARACTERIZED by innovation, energy and progress, transforming the lives of people who earn degrees, work and make groundbreaking discoveries here. A dramatic trajectory of growth has turned what was once a small teacher preparation college into an internationally recognized research institution that is changing the world.